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Postdoctoral Scientist

Email Address

Laboratory


Dr. Byung C. Ahn


bahn@lsuhsc.edu


O'Callaghan

Dr. Ahn is investigating the molecular biology of alphaherpesvirus gene regulation. His goal is to identify cellular proteins that bind to elements in the promoter of a key viral gene and thereby influence the expression of a major viral regulatory protein. Part of his work concerns the possible role of anti-sense viral RNA molecules in viral gene programming.


Dr. Munish K. Ahuja


mahuja@lsuhsc.edu


Hutt-Fletcher

Dr. Ahuja will investigate the role of Epstein-Barr virus glycoproteins in entry and assembly of virus.


Dr. Malgorzata Bienkowska-Haba


mbienk@lsuhsc.edu


Sapp

Dr. Bienkowska-Haba is investigating the intracellular trafficking of human papillomavirus during infection. Her focus is the identification of cellular compartments which are targeted by the minor capsid protein L2 and investigation of L2's role in intracytoplasmic trafficking and nuclear translocation of the viral genome.


Dr. Gary C.T. Chan


gchan@lsuhsc.edu


Yurochko

Dr. Chan is investigating the molecular changes in monocytes that promote viral dissemination and are associated with viral pathogenesis.


Dr. Harish Changotra

hchang@lsuhsc.edu


Karst

Dr. Changotra is studying the molecular mechanisms of replication of noroviruses.  His goal is to determine if the RNA genome of murine norovirus 1, MNV-1, adopts a lariat conformation during intracellular viral replication and, if so, what the function of this structure is.  He is also involved in a project to understand the mechanism(s) by which Type I interferon signaling inhibits MNV-1 replication.


Dr. Liudmila S. Chesnokova


lchesn@lsuhsc.edu


Hutt-Fletcher

Dr. Chesnokova's research focuses on the entry of Epstein-Barr virus into epithelial cells. Her goal is to identify the epithelial cell coreceptor that interacts with the virus glycoproteins gH and gL and facilitates fusion between the virus envelope and the cell membrane.


Dr. Ru Jiang


rjiang@lsuhsc.edu


Hutt-Fletcher

Dr. Jiang is researching the roles played by Epstein-Barr virus glycoproteins in virus transmission, tropism and spread within the host.

 

Dr. Runfeng Jing

rjing@lsuhsc.edu Stokes

Based on the key role platelets play in cardiovascular disease, Dr Jing’s work is focused on how platelets may be activated during CMV infection. Her goal is to identify the mechanisms that underlie the contribution of platelets to the microvascular dysfunction that is observed during cytomegalovirus infection.

 

Dr. Mikhail Khoretonenko

mkhore@lsuhsc.edu Stokes

Dr. Khoretonenko is investigating the pro-inflammatory potential of cytomegalovirus with a view to understanding how this virus contributes to cardiovascular disease. His primary focus is the role of endothelium-platelet interactions in vascular responses to CMV infection either alone or in combination with other cardiovascular risk factors. 

 

Dr. Seong-man Kim

 

skim5@lsuhsc.edu

 

Sapp

Dr. Kim is studying the early events of papillomavirus infection including virus and receptor interactions.


Dr. Haiyan Li


hli@lsuhsc.edu


Tibbetts

Dr. Li is investigating the molecular biology of chronic gammaherpesvirus infection.  She is using mutant viruses that are replication-defective to establish in vivo and in vitro systems to study latency.  Her goals are to define and characterize novel viral genes that are involved in latency and pathogenesis, and to determine some of the molecular mechanisms used by host cells to govern the establishment of latency.


Dr. Ravi Kumar Patnaikuni


rpatna@lsuhsc.edu


Klimstra

Dr. Patnaikuni will investigate the mechanisms of action of type I interferon-induced antiviral genes.


Dr. Jun (Tracy) Yin


jyin@lsuhsc.edu


Ryman

Dr. Yin will assess and optimize the use of alphaviruses as oncolytic viruses for cancer gene therapy.

 

Dr. Fangfang Zhang

  Sixbey
The cellular transcription factor Pax5 has been implicated in the commitment of lymphoid progenitors to the B lymphocyte lineage, in the transcriptional control of B cell development and function, and as a contributor to human B cell malignancies when deregulated by chromosomal translocation. Dr. Zhang is studying the interaction of the Epstein-Barr virus lytic cycle protein Zta with Pax5 in regard to pathological implications it may have at this stage of the virus life cycle.


Dr. Yugen Zhang


yzhan1@lsuhsc.edu


Ryman

Dr. Zhang will investigate the role of the innate immune response (particularly type I interferon) in the control of alphavirus virulence. His goals are to characterize the interferon induction mechanism(s) and to identify potential viral interferon antagonists.


Dr. Yunfei Zhang


yzhang1@lsuhsc.edu


O'Callaghan

Dr. Zhang is investigating the mechanism by which the trans-activation domain of the major regulatory protein of equine herpesvirus-1 functions.

The project described was supported by NIH Grant Number
P20RR018724 from the National Center for Research Resources.

 

 


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