Postdoctoral Scientist |
Email Address |
Laboratory |
Dr. Byung C. Ahn
|
bahn@lsuhsc.edu
|
O'Callaghan
|
|
Dr. Ahn is investigating the molecular biology of alphaherpesvirus gene regulation. His goal is to identify the role of anti-sense viral RNA in viral gene programming. His initial findings reveal that a small RNA that is anti-sense to the mRNA of the major regulatory protein is processed to micro RNAS that target the mRNA of the sole immediate-early regulatory gene. |
Dr. Munish K. Ahuja
|
mahuja@lsuhsc.edu
|
Hutt-Fletcher
|
Dr. Ahuja will investigate the role of Epstein-Barr virus glycoproteins in entry and assembly of virus. |
Dr. Malgorzata Bienkowska-Haba
|
mbienk@lsuhsc.edu
|
Sapp
|
Dr. Bienkowska-Haba is investigating the intracellular trafficking of human papillomavirus during infection. Her focus is the identification of cellular compartments which are targeted by the minor capsid protein L2 and investigation of L2's role in intracytoplasmic trafficking and nuclear translocation of the viral genome. |
Dr. Rebecca L. Bigelow
|
rbigel@lsuhsc.edu
|
Cardelli
|
Dr. Bigelow's research will involve working on a protein thought to be important in the regulation of breast cancer progression. |
Dr. Gary C.T. Chan
|
gchan@lsuhsc.edu
|
Yurochko
|
Dr. Chan is investigating the molecular changes in monocytes that promote viral dissemination and are associated with viral pathogenesis. |
Dr. Harish Changotra
|
hchang@lsuhsc.edu
|
Karst
|
Dr. Changotra is studying the molecular mechanisms of replication of noroviruses. His goal is to determine if the RNA genome of murine norovirus 1, MNV-1, adopts a lariat conformation during intracellular viral replication and, if so, what the function of this structure is. He is also involved in a project to understand the mechanism(s) by which Type I interferon signaling inhibits MNV-1 replication. |
Dr. Liudmila S. Chesnokova
|
lchesn@lsuhsc.edu
|
Hutt-Fletcher
|
Dr. Chesnokova's research focuses on the entry of Epstein-Barr virus into epithelial cells. Her goal is to identify the epithelial cell coreceptor that interacts with the virus glycoproteins gH and gL and facilitates fusion between the virus envelope and the cell membrane. |
Dr. Ellen F. Hildebrant
|
ehilde@lsuhsc.edu
|
McGee
|
| Dr. Hildebrandt is investigating the influence of the pathogen Helicobacter pylori upon host gene expression profiles, with particular focus on the effects of the bacterial enzyme, arginase, which contributes to the inflammatory response and to disease progression. Gene expression is being studied in T-lymphocytes and in animal models of gastritis and gastric cancer. |
Dr. Ru Jiang
|
rjiang@lsuhsc.edu
|
Hutt-Fletcher
|
Dr. Jiang is researching the roles played by Epstein-Barr virus glycoproteins in virus transmission, tropism and spread within the host. |
Dr. Seong-man (Seth) Kim
|
skim5@lsuhsc.edu
|
Sapp
|
Dr. Kim is studying the early events of papillomavirus infection including virus and receptor interactions. |
Dr. Haiyan Li
|
hli@lsuhsc.edu
|
Tibbetts
|
Dr. Li is investigating the molecular biology of chronic gammaherpesvirus infection. She is using mutant viruses that are replication-defective to establish in vivo and in vitro systems to study latency. Her goals are to define and characterize novel viral genes that are involved in latency and pathogenesis, and to determine some of the molecular mechanisms used by host cells to govern the establishment of latency. |
Dr. Guangliang Liu
|
gliu1@lsuhsc.edu
|
Karst
|
Dr. Liu is interested in defining the importance of persistent murine norovirus infection on the impairment of memory immune responses. His project will test the hypothesis that infection of dendritic cells alters the ability of the cell to present antigen to and activate T cells, leading to a lack of protective mucosal immunity.
|
Dr. Karla A. McInnis
|
kmcinn@lsuhsc.edu
|
Testerman
|
Dr. McInnis is investigating the interactions between serum proteins and Helicobacter pylori. Her goal is to determine which specific serum proteins influence H. pylori growth, morphology, and adherence properties. She is also using microarray analysis to determine which H. pylori genes are regulated in response to serum. These projects will advance the understanding of the interplay between H. pylori and host tissue during ulcer formation and invasion of the gastric mucosa.
|
Dr. Jun Yin
|
jyin@lsuhsc.edu
|
Ryman
|
| Dr. Yin will assess and optimize the use of alphaviruses as oncolytic viruses for cancer gene therapy. |
Dr. Fangfang Zhang
|
fzhan1@lsuhsc.edu
|
Sixbey
|
The cellular transcription factor Pax5 has been implicated in the commitment of lymphoid progenitors to the B lymphocyte lineage, the transcriptional control of subsequent B cell development and function, as well as a role in human B cell malignancies when deregulated by chromosomal translocation. Dr. Zhang is studying the interaction of the Epstein-Barr virus lytic cycle protein Zta with Pax5 in regard to pathological implications it may have at this stage of the virus life cycle.
|
Dr. Yugen Zhang
|
yzhan1@lsuhsc.edu
|
Ryman
|
Dr. Zhang is investigating the role of the innate immune response (particularly type I interferon) in the determination of alphavirus virulence. His goals are to characterize the nature of interferon-induced antiviral effectors that control alphavirus replication in infected hosts.
|
Dr. Yunfei Zhang
|
yzhang1@lsuhsc.edu
|
O'Callaghan
|
| Dr. Zhang is investigating the mechanism by which the trans-activation domain of the major regulatory protein of equine herpesvirus-1 functions. |
Dr. Huijuan Zhou
|
hzhou@lsuhsc.edu
|
Wolcott
|
| Dr. Zhou is researching the effects of alcohol consumption on hematopoiesis and lymphopoiesis in neonatal and adult bone marrow. |
