Kendra Jones

BS Microbiology, Colorado State Univ, 2013
Research:
Rotavirus is one of the leading causes of dehydrating diarrheal disease in children and infants. Replication of rotavirus in infected cells is dependent upon the virus’s ability to evade the host immune response, particularly interferon. Rotavirus protein NSP1 has been shown to subvert the interferon response by targeting pathway intermediates for degradation. The ability of NSP1 to degrade these components has been hypothesized to play a role in the host restriction of rotavirus strains. My project focuses on the relationship between NSP1 interferon evasion mechanisms and host restriction in rotavirus replication. 

Supported by a grant from the National Institute of General Medical Sciences (P30-GM110703).