Samantha S. Dykes

B.S., Biology, 2009, Sul Ross State University
Tumor cell invasion is a complex process and is thought to be mediated, in part, by the release of lysosome associated proteases into the tumor microenvironment.  Our lab has identified a novel connection between the position of lysosomes within tumor cells, cathepsin secretion, and tumor invasion.  My project focuses on delineating the mechanism by which lysosomes move within tumor cells in response to stimulation with Epidermal Growth Factor (EGF) and understanding how this process contributes to tumor invasion. 

Supported by a grant from the National Institute of General Medical Sciences (P30-GM110703).